21. You might try a prescription. Topical antibiotics are available only with a prescription and work by killing the bacteria on your skin that cause acne, and by reducing inflammation. Some examples of topical antibiotics are erythromycin and clindamycin. Your doctor may prescribe you them in conjunction with another topical treatment such as one containing benzoyl peroxide or a retinoid such as Retin-A.

Buying a generic face wash won’t necessarily improve your complexion; for a cleanser to be most effective, you have to pay attention to your skin’s needs and pick the ingredients accordingly. If your skin tends to be oily, choose products with salicylic acid, benzoyl peroxide, or glycolic acid. For sensitive skin, look for cleansers with lactic acid or hydrating ingredients like glycerin, which aren’t as drying as those made for oilier types.
Although acne remains largely a curse of adolescence, about 20% of all cases occur in adults. Acne commonly starts during puberty between the ages of 10 and 13 and tends to be worse in people with oily skin. Teenage acne usually lasts for five to 10 years, normally going away during the early 20s. It occurs in both sexes, although teenage boys tend to have the most severe cases. Women are more likely than men to have mild to moderate forms into their 30s and beyond.
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While over-the-counter products don’t treat the hormonal component of acne, salicylic acid—a.k.a. willow bark, a.k.a. what aspirin is made of—addresses all other aspects involved in a breakout. “It works,” says Anolik, who recommends using salicylic acid-based products in conjunction with benzoyl peroxide preparations that target acne bacteria with greater strength. Benzoyl peroxide can definitely cause dryness and irritation; if you decide not to use it, know that you’ve got to be even more vigilant about the bacteria on your skin, so cleanse and treat more often. Tea-tree oil preparations like Tammy Fender’s Clarifying Dermagel ($72, goop.com) help. Burt’s Bees Natural Solutions Acne Spot Treatment ($10, burtsbees.com) combines tea tree and salicylic acid for powerful (yet easy on skin) results.
Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
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